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Deriva-Bpo Gel is a combination of two medicines: Adapalene Topical and Benzoyl Peroxide which treat acne (pimples). Adapalene Topical is a form of vitamin A and Benzoyl Peroxide is a keratolytic medicine. Together, they prevent accumulation of the sebum (skin’s natural oil), unblock the pores and allow natural exfoliation of the outer layers of skin. Benzoyl Peroxide additionally penetrates into the skin and kills acne-causing bacteria.